PolyDoms - SIFT and PolyPhen Analysis Database Details

SIFT and PolyPhen Analysis Database Details

Details of databases used for SIFT analysis

    uniref100 from UniProt (Universal Protein Resource) (http://www.pir.uniprot.org/database/download.shtml)
    July 1, 2005
    2,392,904 proteins. 91,269 human proteins.

Details of databases used for PolyPhen analysis

  1. UniProt (ftp://ftp.ebi.ac.uk/pub/databases/uniprot/current_release/knowledgebase/complete)
    July 7, 2005. Release 5.0.
    70,627 human proteins.

  2. nrdb (non-redundant protein sequence database at NCBI) (ftp://ftp.ncbi.nih.gov/blast/db/FASTA/nr.gz)
    July 7, 2005. Version 2.2.11.
    2,543,645 proteins. 120,733 human proteins.

  3. PDB (Protein Data Bank) (ftp://ftp.rcsb.org/pub/pdb/data/structures/all/pdb)
    July 7, 2005.
    66,788 sequences from 31,639 structures.

  4. DSSP (Database of Secondary Stucture in Proteins) (ftp://ftp.ebi.ac.uk/pub/databases/dssp)
    July 7, 2005.
    29,833 structures.